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In French, Cri du chat translates into “cry of the cat”.The symptoms of cri du chat syndrome vary from case to case.

There has also been an association with cri du chat and Hirschsprung’s disease.

Approximately 15-20 percent of affected infants have congenital heart defects.

The most common heart defect is patent ductus arteriosus, a condition in which the passage (ductus) between the blood vessel that leads to the lungs (pulmonary artery) and the major artery of the body (aorta) fails to close after birth.

Affected children also exhibit delays in the acquisition of skills requiring the coordination of muscular and mental activities (psychomotor disability) and moderate to severe intellectual disability.

Additional symptoms affecting different organ systems of the body can also occur.

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